Safety Education Courses in Chinese Education System

At present, school security in China is a problem with huge quantity, great variety and serious consequences. The problem includes disaster, accident calamity, public welfare event, public hygiene event and personal psychological problem. High incidence of security problem reflects the absence of safety education in various types of schools at various levels. The advices are given as following: (a) Education system of Chinese schools should offer safety education courses; (b) A relatively well-developed system of safety education in Chinese school should be established; (c) Laws and regulations related to safety should be carried out certainly

MicroRNA-140-5p inhibits cellular proliferation, migration and invasion by downregulating AKT/STAT3/NF-κB pathway in breast carcinoma cells

MicroRNA-140-5p (miR-140-5p) plays a pivotal role in human cancers. However, its role and molecular mechanisms in breast carcinoma are not fully explored. Using miR-140-5p transfected breast cancer cell line MDA-MB-231, several in vitro experiments were performed and described in this paper. They consist of the cell proliferation assay, wound healing assay, transwell assay, colony formation assays and qRTPCR. Expression levels of target proteins were determined using western blotting. In addition, experiments on animal models were performed to study the possible role of miR-140-5p in tumorigenesis of breast carcinoma cells. The induction of experimental breast tumor in mice model was achieved through the incorporation of MDA-MB-231 tumor cells subcutaneously into the middle left side of the mice. The results showed that miR-140-5p up-regulation significantly suppresses proliferation, cellular invasion and migration of breast carcinoma cells. Furthermore, miR-140-5p up-regulation stops breast cancer cells at G0/G1 phase. The results of the animal model indicated that up-regulation of miR-140-5p suppresses its tumorigenic ability. Moreover, we also found that miR-140-5p up-regulation reduces the phosphorylation level of STAT3, p65, and AKT. In addition, miR-140-5p overexpression significantly decreases CDK2 expression while increasing E-cadherin expression level. These data revealed that miR-140-5p suppressed tumor progression of breast carcinoma cells through inhibition of the AKT/STAT3/NF-κB pathway. Taken the present study results together, we can conclude that miR-140-5p may act as a novel target in microRNA-targeting anticancer strategy for the treatment of breast cancer

Adaptive NN Control for Multisteering Plane Aircraft with Dead Zone or Backlash Input Nonlinearity

Considering that many factors such as actuator input dead zone, backlash, and external disturbance could affect the exactness of trajectory tracking, therewith a robust adaptive neural network control scheme on the basis of control allocation is proposed for the sake of tracking control of multisteering plane aircraft with actuator input dead zone or backlash nonlinearity. First of all, an actuator input dead zone or backlash nonlinearity control assignment model is established and the control allocation equation is derived. Secondly, the system nonlinear uncertainty is compensated by means of radial basis function neural network, and a robust term is introduced to achieve robustness against external disturbance and system errors. Finally, by utilizing Lyapunov stability theorem, it has been proved that all the signals in the closed-loop system are bounded, and the tracking error converges to a small residual set asymptotically. Simulation results on ICE101 multisteering plane aircraft demonstrate the outstanding tracking performance and strong robustness as well as effectiveness of the proposed approach, which can effectively overcome the adverse influence of dead zone, backlash nonlinearity, and external disturbance on the system

Reusable oxidation catalysis using metal-monocatecholato species in a robust metal-organic framework.

An isolated metal-monocatecholato moiety has been achieved in a highly robust metal-organic framework (MOF) by two fundamentally different postsynthetic strategies: postsynthetic deprotection (PSD) and postsynthetic exchange (PSE). Compared with PSD, PSE proved to be a more facile and efficient functionalization approach to access MOFs that could not be directly synthesized under solvothermal conditions. Metalation of the catechol functionality residing in the MOFs resulted in unprecedented Fe-monocatecholato and Cr-monocatecholato species, which were characterized by X-ray absorption spectroscopy, X-band electron paramagnetic resonance spectroscopy, and (57)Fe Mössbauer spectroscopy. The resulting materials are among the first examples of Zr(IV)-based UiO MOFs (UiO = University of Oslo) with coordinatively unsaturated active metal centers. Importantly, the Cr-metalated MOFs are active and efficient catalysts for the oxidation of alcohols to ketones using a wide range of substrates. Catalysis could be achieved with very low metal loadings (0.5-1 mol %). Unlike zeolite-supported, Cr-exchange oxidation catalysts, the MOF-based catalysts reported here are completely recyclable and reusable, which may make them attractive catalysts for 'green' chemistry processes

Radiative transitions in charmonium from Nf=2N_f=2 twisted mass lattice QCD

We present a study for charmonium radiative transitions: $J/\psi\rightarrow\eta_c\gamma$, $\chi_{c0}\rightarrow J/\Psi\gamma$ and $h_c\rightarrow\eta_c\gamma$ using $N_f=2$ twisted mass lattice QCD gauge configurations. The single-quark vector form factors for $\eta_c$ and $\chi_{c0}$ are also determined. The simulation is performed at a lattice spacing of $a= 0.06666$ fm and the lattice size is $32^3\times 64$. After extrapolation of lattice data at nonzero $Q^2$ to 0, we compare our results with previous quenched lattice results and the available experimental values.Comment: typeset with revtex, 15 pages, 11 figures, 4 table

A Quenched Study of SU(3) Glueballs at Finite Temperature

Thermal properties of glueballs in SU(3) Yang-Mills theory are investigated in a large temperature range from $0.3T_c$ to $1.9T_c$ on anisotropic lattices. The glueball operators are optimized for the projection of the ground states by the variational method with a smearing scheme. Their thermal correlators are calculated in all 20 symmetry channels. It is found in all channels that the pole masses $M_G$ of glueballs remain almost constant when the temperature is approaching the critical temperature $T_c$ from below, and start to reduce gradually with the temperature going above $T_c$. The correlators in the $0^{++}$, $0^{-+}$, and $2^{++}$ channels are also analyzed based on the Breit-Wigner \emph{Ansatz} by assuming a thermal width $\Gamma$ to the pole mass $\omega_0$ of each thermal glueball ground state. While the values of $\omega_0$ are insensitive to $T$ in the whole temperature range, the thermal widths $\Gamma$ exhibit distinct behaviors at temperatures below and above $T_c$. The widths are very small (approximately few percent of $\omega_0$ or even smaller) when $TT_c$ and reach values of roughly $\Gamma\sim \omega_0/2$ at $T\approx 1.9T_c$.Comment: 13 pages, 38 figure

[μ-1,4-Bis(1,2,4-triazol-1-ylmeth­yl)benzene]­bis­[aqua­(pyridine-2,6-dicarboxyl­ato)copper(II)] monohydrate

The title compound, [Cu2(C7H3NO4)2(C12H12N6)(H2O)2]·H2O, displays a discrete dinuclear structure, in which the central CuII atom is five-coordinated in a distorted square-based pyramidal coordination geometry and the flexible ligand 1,4-bis­(1,2,4-triazol-1-ylmeth­yl)benzene adopts a bis-monodentate bridging mode linking the CuII atoms. It is further assembled by O—H⋯O hydrogen-bond inter­actions involving both the coordinated and uncoordinated water molecules. The latter exhibits half-occupancy